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Direct action of parathyroid hormone include everything EXCEPT
Question

Direct action of parathyroid hormone include everything EXCEPT

A.

Increased resorption of calcium from bone

B.

Increased absorption of calcium from intestine

C.

Increased reabsorption of calcium from kidney

D.

Increased production of 1,25 dihydroxy Vitamin D

Correct option is B

Parathyroid hormone (PTH) acts directly on bones and kidneys but not on the intestine. The increased calcium absorption from the intestine is an indirect effect via increased production of active Vitamin D. Explanation of each option: • (a) Increased resorption of calcium from bone – True. PTH stimulates osteoclasts to break down bone and release calcium into the bloodstream. • (b) Increased absorption of calcium from intestine – Incorrect (Correct Answer). This is an indirect effect. PTH stimulates the production of active Vitamin D (calcitriol), which then enhances calcium absorption in the intestines. • (c) Increased reabsorption of calcium from kidney – True. PTH increases calcium reabsorption in the distal tubules, reducing urinary calcium loss. • (d) Increased production of 1,25 dihydroxy Vitamin D – True. PTH stimulates renal 1-alpha-hydroxylase to convert 25(OH)D to its active form, calcitriol, which helps absorb calcium from the gut.

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