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A patient with superficial bladder cancer is treated with intravesical mitomycin C. After instillation, the nurse advises the patient to:
Question

A patient with superficial bladder cancer is treated with intravesical mitomycin C. After instillation, the nurse advises the patient to:

A.

Void urine immediately to avoid toxicity

B.

Hold urine for 1–2 hours before voiding

C.

Drink large amounts of water immediately after instillation

D.

Lie in supine position for 12 hours

Correct option is B

Mitomycin requires adequate contact time with bladder mucosa. Patients are instructed to retain urine for 1–2 hours post-instillation for maximum efficacy.
Explanation of options: (a) ✘ Immediate voiding reduces therapeutic effect. (b) ✔ Correct; 1–2 hr retention improves mucosal exposure. (c) ✘ Hydration is good after therapy but not immediately. (d) ✘ Positioning for hours is not part of protocol.

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