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    A patient receiving a blood transfusion develops chills, rigors, dyspnea, and hypotension. What is the most appropriate immediate management?
    Question

    A patient receiving a blood transfusion develops chills, rigors, dyspnea, and hypotension. What is the most appropriate immediate management?

    A.

    Slow down the transfusion and monitor vitals

    B.

    Continue transfusion with antihistamines

    C.

    Stop transfusion and administer IV hydrocortisone ± antihistamine

    D.

    Switch to another blood bag immediately

    Correct option is C

    In suspected transfusion reaction (especially anaphylaxis or severe febrile reaction), the transfusion must be stopped immediately and managed with IV steroids ± antihistamines.
    Explanation of options: (a) ✘ Slowing transfusion is unsafe; must be stopped. (b) ✘ Continuing increases reaction risk; wrong. (c) ✔ Correct; stop transfusion + steroids/antihistamine is standard. (d) ✘ Switching bags risks recurrence if reaction not clarified.

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