Correct option is C
250 mg = 10 ml per dose. Twice daily = 20 ml per day. For 5 days, total = 100 ml needed. Since 1 bottle = 45 ml, 100 ÷ 45 ≈ 2.22, meaning 3 bottles not sufficient, 4 bottles required.
Explanation of options: (a) ✘ Two bottles provide only 90 ml, which is 10 ml less than required. The course will not be completed. (b) ✘ Three bottles = 135 ml, but when dispensing, a full extra bottle must be given to cover exact need. Otherwise shortage risk exists. (c) ✔ Correct; 4 bottles ensure a minimum of 100 ml available, covering the full prescription without risk of shortage. (d) ✘ Five bottles = 225 ml, which is much more than needed, leading to wastage.