Which syndrome causes a thick hump between the shoulders, a round face and pink or purple stretch marks on the skin? 

Correct option is C

Cushing syndrome is caused by prolonged exposure to high levels of cortisol, either due to overproduction by the body or as a side effect of corticosteroid medications. The hallmark symptoms include:

• A thick hump between the shoulders (buffalo hump).
• A round face (moon face).
• Pink or purple stretch marks (striae) on the skin, especially on the abdomen, thighs, and arms.

Other symptoms may include weight gain, thinning skin, easy bruising, muscle weakness, and high blood pressure.

Additional Information:

• Cushing syndrome can occur due to conditions like Cushing's disease (when a pituitary tumor produces excess ACTH) or long-term use of glucocorticoids.
• Diagnosis typically involves hormonal tests and imaging studies, and treatment depends on the underlying cause (e.g., surgery, medication, or reducing steroid use).

Other Options:

• Down syndrome: A genetic disorder caused by an extra copy of chromosome 21. It is characterized by distinct facial features, developmental delays, and intellectual disabilities, not the symptoms listed in the question.
• Angelman syndrome: A genetic disorder affecting the nervous system, leading to developmental delays, seizures, and a happy demeanor, but not the physical symptoms mentioned.
• Marfan syndrome: A genetic disorder affecting connective tissue, often resulting in tall stature, long limbs, and cardiovascular problems, but not the specific symptoms of a hump or stretch marks.