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    Which of the following is broad spectrum antibiotic?
    Question

    Which of the following is broad spectrum antibiotic?

    A.

    Erythromycin

    B.

    Penicillin G

    C.

    Chloramphenicol

    D.

    Gentamycin

    Correct option is C

    Correct Answer: (c) Chloramphenicol
    Explanation:
    · Chloramphenicol is a broad-spectrum antibiotic, meaning it is effective against a wide range of both gram-positive and gram-negative bacteria.
    · It works by inhibiting protein synthesis in bacteria and is used for serious infections like typhoid fever and meningitis.
    Information Booster:
    · Broad-spectrum antibiotics target diverse bacterial groups, making them useful when the exact pathogen is unknown.
    · Chloramphenicol can cross the blood–brain barrier, making it effective for CNS infections.
    · It must be used cautiously due to potential side effects like bone marrow suppression.
    Additional Knowledge :
    · (a) Erythromycin:
    · A narrow-spectrum antibiotic mainly effective against gram-positive bacteria.
    · (b) Penicillin G:
    · Also narrow-spectrum, effective mostly against gram-positive bacteria; destroyed by stomach acid, hence given by injection.
    · (d) Gentamycin:
    · Broadly active against gram-negative bacteria, but not classified as a true broad-spectrum antibiotic across both bacterial types.

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