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Which of these contracts the smooth muscles in the bronchi and gut and relaxes other muscles, such as those in the walls of the fine blood vessels?
Question

Which of these contracts the smooth muscles in the bronchi and gut and relaxes other muscles, such as those in the walls of the fine blood vessels?

A.

Tetradotoxin

B.

Histamine

C.

Brompheniramine

D.

Chlordiazepoxide

Correct option is B

Correct Answer: (b) Histamine
Explanation:
· Histamine is a biological amine released during allergic reactions and inflammatory responses.
· It contracts smooth muscles in the bronchi and gut, leading to bronchoconstriction and intestinal spasms.
· At the same time, it relaxes smooth muscles in the walls of fine blood vessels, causing vasodilation.
Information Booster:
· Effects of histamine:
· Bronchoconstriction → difficulty in breathing (seen in asthma, allergies).
· Increased gastric secretion → stimulates stomach acid.
· Vasodilation and increased capillary permeability → redness, swelling, and fall in blood pressure.
· Antihistamines (like brompheniramine) block these effects during allergic reactions.
Additional Knowledge:
· (a) Tetradotoxin: A potent neurotoxin found in pufferfish; blocks sodium channels.
· (c) Brompheniramine: An antihistamine used to treat allergies; opposes the action of histamine.
· (d) Chlordiazepoxide: A benzodiazepine used for anxiety and sedation.

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