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Which of the following is the drug of choice for treating Chlamydia infection?
Question

Which of the following is the drug of choice for treating Chlamydia infection?

A.

Amoxicillin

B.

Erythromycin

C.

Ciprofloxacin

D.

Cotrimoxazole

Correct option is B


Ans. (b) Sol. Erythromycin is one of the preferred antibiotics for treating Chlamydia infection, especially in pregnant women and infants with Chlamydia-related pneumonia or conjunctivitis. Chlamydia trachomatis is an intracellular bacterium, and macrolide antibiotics like Azithromycin (preferred single-dose treatment) or Doxycycline (7-day regimen) are the first-line treatments. However, Erythromycin is used as an alternative in cases where these drugs are contraindicated.
Explanation of Other Options:
· (a) Amoxicillin: Though a broad-spectrum penicillin, it is less effective against intracellular bacteria like Chlamydia and is not a first-line treatment.
· (c) Ciprofloxacin: A fluoroquinolone, primarily used for Gram-negative bacterial infections, but not recommended for Chlamydia due to lower efficacy.
· (d) Cotrimoxazole: A combination of Trimethoprim and Sulfamethoxazole, mainly used for urinary tract infections and pneumocystis pneumonia, but ineffective against Chlamydia.

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