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Which of the following enters the Krebs cycle:
Question

Which of the following enters the Krebs cycle:

A.

Malate

B.

Acetyl Co A

C.

Oxaloacetate

D.

None of these

Correct option is B

The correct answer is: (B) Acetyl CoA
The Krebs cycle (Citric Acid Cycle or TCA Cycle) is a crucial part of cellular respiration that takes place in the mitochondrial matrix.
The cycle begins when Acetyl CoA (Acetyl Coenzyme A) combines with Oxaloacetate to form Citrate (Citric Acid), which then undergoes a series of reactions to generate ATP, NADH, and FADH₂.
Acetyl CoA is derived from:
  • Glycolysis (via Pyruvate)

  • Beta-oxidation of fatty acids

  • Amino acid metabolism

Information Booster:
  1. Takes place in the mitochondrial matrix.

  2. Starts with Acetyl CoA combining with Oxaloacetate to form Citrate.

  3. Produces ATP, NADH, FADH₂, and CO₂, which are used in energy production.

  4. Plays a key role in aerobic respiration by providing high-energy electrons for the Electron Transport Chain (ETC).

  5. Regulated by enzyme activity and availability of substrates (like Acetyl CoA and NAD⁺).​

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