Which of the following drugs is mainly used in the management of glaucoma?

Correct option is B

Acetazolamide is a carbonic anhydrase inhibitor that decreases aqueous humor production, thereby lowering intraocular pressure in glaucoma patients.
Explanation of options: (a) ✘ Penicillin is an antibiotic, unrelated to glaucoma treatment. (b) ✔ Acetazolamide directly reduces intraocular pressure. (c) ✘ Atropine dilates the pupil and may increase pressure. (d) ✘ Tropicamide is a mydriatic used in eye exams, not glaucoma management.