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Which of the following diabetes drugs acts by decreasing the amount of glucose produced by the liver?
Question

Which of the following diabetes drugs acts by decreasing the amount of glucose produced by the liver?

A.

Sulfonylureas

B.

Meglitinides

C.

Biguanides

D.

Alpha-glucosidase inhibitors

Correct option is C


Ans. (c) Sol. Biguanides, such as Metformin, decrease glucose production in the liver, making them effective in managing Type 2 diabetes.
Explanation of each option:
· (a) Sulfonylureas – Stimulate the pancreas to release more insulin, but do not reduce glucose production by the liver.
· (b) Meglitinides – Stimulate insulin release after meals but do not impact liver glucose production.
· (c) Biguanides – Correct answer. Metformin, a biguanide, reduces hepatic glucose production and improves insulin sensitivity.
· (d) Alpha-glucosidase inhibitors – Slow down carbohydrate absorption but do not affect liver glucose production.

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