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Which gland or organ doesn’t work right in type 1 diabetes?
Question

Which gland or organ doesn’t work right in type 1 diabetes?

A.

Pituitary gland

B.

Pancreas

C.

Adrenal glands

D.

Kidneys

Correct option is B


Sol. In type 1 diabetes, the pancreas fails to produce adequate or any insulin due to the autoimmune destruction of beta cells in the islets of Langerhans. Insulin is essential for regulating blood glucose levels, and without it, glucose builds up in the bloodstream instead of being absorbed by the cells. Type 1 diabetes typically appears in childhood or adolescence and requires lifelong insulin therapy. The pancreas is the primary organ impacted in this condition, and its function is crucial for metabolic balance.
Explanation of each option:
· (a) Pituitary gland – Incorrect. Though the pituitary controls many hormones, it is not involved in insulin production or regulation of blood glucose in Type 1 diabetes.
· (b) Pancreas – Correct. The pancreas houses the beta cells which produce insulin. In Type 1 diabetes, these cells are attacked by the immune system, causing insulin deficiency.
· (c) Adrenal glands – Incorrect. These glands release hormones like cortisol and adrenaline, which can influence glucose levels indirectly but are not responsible for insulin production.
· (d) Kidneys – Incorrect. While diabetes affects kidney function over time (diabetic nephropathy), kidneys are not the source of the insulin problem in Type 1 diabetes.

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