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Which drug is effective for iron chelation therapy in beta thalassemia?
Question

Which drug is effective for iron chelation therapy in beta thalassemia?

A.

Deferoxamine

B.

Trimethoprim

C.

Immunoglobulins

D.

Dextromethorphan

Correct option is A

Deferoxamine is an iron-chelating agent used to treat iron overload in patients with beta thalassemia who require frequent blood transfusions. Chronic transfusions lead to iron accumulation in vital organs, which can be toxic. Deferoxamine binds excess iron and promotes its excretion, preventing complications such as heart and liver damage.
Explanation of options: (a) Deferoxamine – This is the correct answer. It is a standard therapy for managing transfusion-related iron overload in thalassemia patients. (b) Trimethoprim – This is an antibiotic used in combination with sulfamethoxazole; it has no role in iron chelation. (c) Immunoglobulins – Used in immune deficiencies or autoimmune disorders; they do not help with iron removal. (d) Dextromethorphan – A cough suppressant, unrelated to iron metabolism or thalassemia treatment.

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