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Which among the following is the correct order of changes in the membrane potential during an action potential?
Question

Which among the following is the correct order of changes in the membrane potential during an action potential?

A.

De-polarization, Hyperpolarization, Re-polarization, Polarization

B.

Hyperpolarization, De-polarization, Re-polarization, Polarization

C.

Polarization, De-polarization, Hyperpolarization, Re-polarization

D.

Polarization, Hyper polarization, De-polarization, Re-polarization

Correct option is C

The action potential follows this sequence: Polarization (resting state at -70mV) → Depolarization (membrane becomes less negative, reaching +40mV) → Hyperpolarization (overshoots below resting potential) → Repolarization (returns to resting state).

Information Booster:
• Polarization (Resting State): Neuron membrane is at resting potential (~-70mV), with more negative charges inside
• Depolarization: Sodium channels open, Na+ ions rush in, membrane potential becomes positive (+30 to +40mV)
• Hyperpolarization: Potassium channels remain open too long, K+ efflux causes membrane to become more negative than resting potential (~-80 to -90mV)
• Repolarization: Membrane gradually returns to resting potential as ion pumps restore normal distribution
• The entire action potential cycle takes approximately 1-2 milliseconds
• The refractory period during and after an action potential prevents backward propagation and limits firing frequency

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