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When was Singer and Nicolson's fluid mosaic model accepted as the foundational model for the interpretation of existing data on membrane proteins and
Question

When was Singer and Nicolson's fluid mosaic model accepted as the foundational model for the interpretation of existing data on membrane proteins and lipids, and their dynamics?

A.

1952

B.

1972

C.

1942

D.

1982

Correct option is B

  • The fluid mosaic model was proposed by Singer and Nicolson in 1972 and quickly became the foundational framework for understanding the structure and dynamics of cellular membranes.
  • This model describes the membrane as a fluid bilayer of lipids with proteins embedded in or associated with the bilayer, allowing for lateral movement.

Additional Information:

  • The fluid mosaic model revolutionized the understanding of biological membranes, explaining how the membrane's fluid nature allows dynamic processes such as protein movement, membrane fusion, and selective permeability.
  • It provided insights into the amphipathic nature of lipids, where hydrophilic heads face outward and hydrophobic tails face inward, forming a bilayer.
  • The model also accounts for the diverse functions of integral and peripheral proteins, such as signal transduction, transport, and cell recognition.

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