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    What is the antidote for dopamine?
    Question

    What is the antidote for dopamine?

    A.

    Dobutamine

    B.

    Phentolamine

    C.

    Epinephrine

    D.

    Norepinephrine

    Correct option is B

    Phentolamine is a non-selective alpha-adrenergic antagonist used as an antidote for dopamine extravasation. When dopamine leaks into surrounding tissue, it causes vasoconstriction and necrosis. Phentolamine counteracts this effect by dilating the blood vessels, preventing tissue damage.
    Explanation of options: (a) ✘ Dobutamine – A beta-agonist used in heart failure, not an antidote for dopamine. (b) ✔ Phentolamine – Alpha-blocker that reverses vasoconstriction caused by dopamine. (c) ✘ Epinephrine – A vasoconstrictor, would worsen tissue ischemia if used here. (d) ✘ Norepinephrine – Also causes vasoconstriction; not suitable as an antidote.

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