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​The figure below shows the genes (a, b, c, d, f, l, m n) that are expressed in cell types 1, 2 and 3 because of the concentration of morphogen signal
Question

The figure below shows the genes (a, b, c, d, f, l, m n) that are expressed in cell types 1, 2 and 3 because of the concentration of morphogen signaling received by these cells.

Which one of the following statements is correct about the pattern of gene expression induced by the morphogen?

The transcription factor activated by the morphogen has:

A.

higher affinity for regulatory region of a than that of d.

B.

higher affinity for regulatory region of f than that of c.

C.

same affinity for regulatory regions of a and b.

D.

lower affinity for regulatory region of m than that of c.

Correct option is B

EXPLANATION-

The figure shows a classic morphogen gradient, where different genes are expressed in different cell types based on morphogen concentration thresholds:
Cell type 1 (high morphogen levels): expresses genes a, b, c
Cell type 2 (medium morphogen levels): expresses genes d, b, f
Cell type 3 (low morphogen levels): expresses genes l, m, n

Gene f is expressed in cell type 2 and 3, meaning it requires lower morphogen levels (i.e., higher affinity).
Gene c is expressed only in cell type 1, requiring high morphogen levels (i.e., lower affinity).

The transcription factor must have higher affinity for the regulatory region of f (activated at lower morphogen concentration) than that of c.

So, the correct option is (b)

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