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The active site on the normal actin filament of the relaxed muscle are inhibited by the:
Question

The active site on the normal actin filament of the relaxed muscle are inhibited by the:

A.

Calcium ions

B.

Magnesium ions and ATP

C.

Troponin-Tropomyosin complex

D.

Polymerised-G actin molecule

Correct option is C

In relaxed muscles, the troponin-tropomyosin complex covers the myosin-binding sites on actin, preventing contraction. Upon calcium binding, this complex shifts to expose the binding sites, allowing contraction.

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