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Sick cell anemia (Sickle cell anemia) is caused by?
Question

Sick cell anemia (Sickle cell anemia) is caused by?

A.

Deficiency of folic acid

B.

Abnormal levels of hemoglobin

C.

Deficiency of iron

D.

Decreased production of red blood cells (RBCs)

Correct option is B

The correct answer is (B) Abnormal levels of hemoglobin

Explanation:

Sickle cell anemia is caused by an abnormal form of hemoglobin, known as hemoglobin S (HbS). This genetic disorder causes the red blood cells to become rigid, sticky, and shaped like a crescent or "sickle," instead of the normal round shape. These sickle-shaped cells can block blood flow, leading to pain, organ damage, and other complications.

Information Booster:
  1. Sickle cell anemia is a genetic disorder, inherited from both parents who carry the sickle cell trait.

  2. The presence of hemoglobin S in red blood cells leads to their characteristic sickle shape, which disrupts blood flow and leads to a reduced ability to carry oxygen.

  3. The condition results in recurrent pain episodes, known as sickle cell crises, and can lead to complications like stroke, organ damage, and infections.

  4. Sickle cell anemia is more common in people of African, Mediterranean, Middle Eastern, and Indian subcontinent descent.

  5. The disorder can be managed with pain relief, blood transfusions, and in some cases, bone marrow transplants.

Additional Information:
  • Deficiency of folic acid : While folic acid deficiency can lead to anemia, it is not the cause of sickle cell anemia.

  • Deficiency of iron : Iron deficiency causes iron-deficiency anemia, which is different from sickle cell anemia.

  • Decreased production of red blood cells : Sickle cell anemia is not caused by the decreased production of red blood cells, but rather by the production of abnormal red blood cells with hemoglobin S.

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