Correct option is A
The correct synonym of the given word is (a)
Offense.
Indignation: Strong displeasure or anger at something considered unjust or offensive. (आक्रोश, रोष)
Example: She was filled with indignation after hearing the unfair decision.
Offense: A feeling of resentment or anger caused by a perceived insult or injustice. (अपमान/आक्रोश)
Example: His remarks caused great offense to the audience.
Synonyms: fury, resentment, outrage, annoyance.
Antonyms: calm, acceptance, contentment, tolerance.
Meanings of all the other given options:
· (b) Designation: A name or title. (पदनाम)
· (c) Resignation: Act of quitting or giving up a job. (इस्तीफा)
· (d) Defence: Protection from harm or attack. (रक्षा)