Match List I with List II

LIST-I (Brain Regions)	LIST-II (Neurotransmitters)
A. Locus coeruleus	I. Acetylcholine
B. Raphe nuclei	II. Dopamine
C. Substantia nigra	III. Serotonin
D. Basal forebrain	IV. Norepinephrine

Correct option is A

The brain regions in List-I are known for producing specific neurotransmitters. Here’s the correct mapping:

A. Locus coeruleus → IV. Norepinephrine (Noradrenaline)
The locus coeruleus, located in the pons, is the primary source of norepinephrine in the brain.
Plays a crucial role in arousal, attention, and stress response.

B. Raphe nuclei → III. Serotonin
The raphe nuclei, located in the brainstem, are the primary source of serotonin (5-HT).
Involved in mood regulation, sleep, and emotional processing.

C. Substantia nigra → II. Dopamine
The substantia nigra, located in the midbrain, produces dopamine, especially in the nigrostriatal pathway.
Plays a key role in motor control, and degeneration of dopamine-producing neurons leads to Parkinson’s disease.

D. Basal forebrain → I. Acetylcholine
The basal forebrain (including the nucleus basalis of Meynert) is a major producer of acetylcholine.
Important for learning, memory, and attention; its dysfunction is linked to Alzheimer’s disease.