Correct option is C
Dioxins are a group of persistent organic pollutants (POPs) formed unintentionally as by-products of industrial processes such as waste incineration, smelting, and chemical manufacturing. They are also released when plastics with brominated flame retardants (BFRs) are burned or re-molded.
Exposure to dioxins has severe toxic effects:
They interfere with brain development, especially in fetuses and children.
They disrupt thyroid hormones and impair immune system function.
Long-term exposure is linked with an increased risk of cancers, particularly due to their ability to alter gene expression. Hence, Option 1 is correct.
Dioxins enter the human body mainly through the oral route (contaminated food, especially animal fats), but they can also enter via dermal absorption and inhalation of contaminated air.
Once inside the body, dioxins are lipophilic and accumulate in fatty tissues, leading to bioaccumulation and long half-lives in the body. Hence, Option 2 is also correct.
Therefore, both Option 1 and Option 2 are correct, making the right answer Option (c).