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Dynein is a microtubule-dependent motor protein essential for cellular processes.Which one of the following statements related to dynein function is I
Question

Dynein is a microtubule-dependent motor protein essential for cellular processes.Which one of the following statements related to dynein function is INCORRECT?

A.

It helps in cilia and flagella beating.

B.

It transports organelles in anterograde direction.

C.

It participates in spindle assembly and positioning.

D.

It interacts with dynactin for efficient transport.

Correct option is B

Correct Answer: 2. It transports organelles in anterograde direction.

Dynein is a microtubule-dependent motor protein that moves cellular cargoes along microtubules. To determine the incorrect statement, let’s evaluate each option based on dynein’s known functions:

Option-by-Option Analysis:

1. It helps in cilia and flagella beating. - Correct.
Axonemal dynein powers the sliding movement of microtubules within cilia and flagella, enabling their beating and movement.
2. It transports organelles in anterograde direction.- Incorrect.
Dynein is responsible for retrograde transport (towards the minus-end of microtubules, typically toward the cell center/nucleus).
Anterograde transport (toward the plus-end, or cell periphery) is carried out by kinesin, not dynein.
3. It participates in spindle assembly and positioning.- Correct.
Cytoplasmic dynein plays a crucial role in mitotic spindle positioning, anchoring of centrosomes, and chromosome movement during cell division.
4. It interacts with dynactin for efficient transport.- Correct.
Dynein requires the dynactin complex for cargo binding, processivity, and directional control during transport.

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