Choose the most suitable option to replace the highlighted part of the sentence:
She insisted me to take the medicine.

Correct option is A

The correct substitution of the highlighted words is (a) that I take the medicine.
Explanation: The verb “insist” is not followed by an object + to-infinitive ( insist me to…). Instead, it is followed by “that + subject + base verb” (subjunctive form) or sometimes “on + V-ing”. Hence, the correct structure is insisted that I take the medicine. This makes the sentence grammatically correct and natural.
Grammatical rule used:
· Insist + that + subject + base form of verb (subjunctive)
· Alternate: Insist on + V-ing (e.g., insisted on taking the medicine)
· Example: She insisted that he apologise immediately.
· Information booster / exceptions:
· In formal English, after insist that, we often use the base verb (take/go/be), not “takes/went”.
· “Insist me to…” is a common learner error; avoid it.