" Arrange the absorption and metabolism of iodine in correct sequence.
A. Iodide
B. Tri-iodothyronine (T3)
C. Dietary Iodide
D. Iodine
E. Thyroxine (T4)
Choose the correct answer from the options given below:

Correct option is B

The absorption and metabolism of iodine follow a distinct pathway in the body, which is essential for the synthesis of thyroid hormones. The steps are:
1. Dietary Iodide (C): Iodine is absorbed primarily in the form of iodide from dietary sources like iodized salt, seafood, and dairy products.
2. Iodide (A): Once ingested, iodide is absorbed in the gastrointestinal tract and transported to the thyroid gland via the bloodstream.
3. Iodine (D): In the thyroid gland, iodide is oxidized to iodine by the enzyme thyroid peroxidase.
4. Thyroxine (T4) (E): Iodine combines with tyrosine residues in the thyroid to produce thyroid hormones, the primary one being Thyroxine (T4).
5. Tri-iodothyronine (T3) (B): Thyroxine (T4) is later converted into the more active form, Tri-iodothyronine (T3), in various tissues of the body. T3 is the active hormone that regulates metabolism​​.
Information Booster:
· Thyroxine (T4) is the major hormone produced by the thyroid gland and is converted into Tri-iodothyronine (T3), the active form that affects metabolism, heart function, digestion, and overall energy balance.
· Iodide (A): This is the ion form of iodine, which is more easily absorbed by the body.
· Tri-iodothyronine (T3) (B): Although only a small amount of T3 is produced directly by the thyroid, it is the more potent and active thyroid hormone, responsible for most of the physiological effects.
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