A few organelles that are present in a eukaryotic cell are mentioned below:

A. Centrosomes

B. Peroxisomes

C. Nucleolus

D. Endosome

Which one of the following options represents organelles that are not membrane-bound?

Following statements were made about protein trafficking in cells:

A. Cargo selection occurs when coat proteins bind to the sorting signals either directly or indirectly via adaptor complexes.
B. Protein export from the ER is exclusively mediated through the COPII-coated vesicles.
C. Identical coat protein is used in the exocytic pathway and/or endocytic pathway.
D. Tethering of the vesicles involves small guanosine triphosphatases (GTPases) of the Rab family.
E. Clathrin-coated vesicles transport proteins from the plasma membrane to the trans-Golgi network to late endosomes.

Which one of the following represents the correct combination of above statements?

​Signal sequences direct proteins to the correct intracellular locations. Which one of the following sequences is typically used to import proteins into the nucleus?​

​Membrane-enclosed organelles often have a characteristic position in the cytosol. In animal cells, for example, the Golgi apparatus is located close to the nucleus. Which component is directly involved in ensuring correct Golgi localization in animal cells?​

Mitochondrial protein synthesis is of prokaryotic origin. Following statements are being made about the ribosomes from bacteria and mitochondria:

A. The bacterial ribosome consists of small and large subunits of 30S and 50S respectively, whereas in mitochondria of mammals these subunits are of 28S and 39S.
B. In the bacterial ribosomes the RNA: protein ratio is about 2:1 whereas in mitochondria ribosomes this ratio is usually 1:2.
C. Both the bacterial and mitochondrial ribosomes consist of 30S and 50S subunits.
D. Both the bacterial and mitochondrial ribosomes consist of RNA and protein in the ratio of 1:1.

Choose the option that represents all correct statements.

​During cytokinesis, a small GTPase, RhoA, localizes to the equatorial membrane above the spindle midzone. The localization/activity of RhoA is potentially modulated by:​

(A) RhoGEF Ect2

(B) Aurora B kinase
(C) PLK1 kinase
(D) MKLP1 kinesin

(E) ATM and ATR

Which one of the following combination contains all correct statements?

Given below are a few statements about nuclear transport.
A. RanGTP levels are higher in the nucleus than the cytoplasm.
B. Nuclear import receptors can shuttle between the nucleus and cytoplasm.
C. NTF2 transports RanGDP into the cytosol.
D. Export of mRNA is not directly dependent on Ran.
E. tRNA and miRNA export is mediated by exportins.

Which one of the following combinations contains all correct statements?

​The movement of proteins bigger than 50 kDa across the nuclear envelope requires:​

The actin-binding proteins regulate microfilament turnover in a eukaryotic system.

Match the actin-binding protein (in column I) with their functions (in column II):

​Choose the CORRECT combination from below:​

Given below are a few steps in clathrin-coated vesicle formation in the secretory pathway:

(A) Receptor-ligand recognition and binding

(B) Recruitment of adapter protein and clathrin

(C) Vesicle formation

(D) Uncoating of clathrin coats

Choose the option that correctly identifies the sequence of events in making a clathrin-coated vesicle:

​The F₁ subunit of F₀F₁ ATP synthase synthesizes ATP from ADP in the mitochondrial inner membrane. Purified F₁ subunit hydrolyses ATP to ADP. Which one of the following reasons explains the difference between the activities of the F₁ subunit in soluble and membrane bound form?​​