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A DNA molecule is completely transcribed into messenger RNA by an RNA polymerase. The base composition of the DNA template strand is G = 24.1%, C = 18
Question

A DNA molecule is completely transcribed into messenger RNA by an RNA polymerase. The base composition of the DNA template strand is G = 24.1%, C = 18.5%, A = 24.6%, T = 32.8%. The base composition of the newly synthesized RNA molecule is:​

A.

G = 24.1%, C = 18.5%, A = 24.6%, U = 32.8%

B.

G = 24.6%, C = 24.1%, A = 18.5%, U = 32.8%

C.

G = 18.5%, C = 24.1%, A = 32.8%, U = 24.6%

D.

G = 32.8%, C = 24.6%, A = 18.5%, U = 24.1%

Correct option is C

RNA is synthesized using the DNA template strand(the non-coding strand) in a process called transcription. The base-pairing rules for RNA are:

  • Adenine (A)in the DNA template strand pairs with uracil (U)in RNA.
  • Thymine (T)in the DNA template strand pairs with adenine (A)in RNA.
  • Cytosine (C)in the DNA template strand pairs with guanine (G)in RNA.
  • Guanine (G)in the DNA template strand pairs with cytosine (C)in RNA.

Given the DNA template base composition:

  • G = 24.1%, C = 18.5%, A = 24.6%, T = 32.8%
    The complementary RNA sequence will be:
  • C in DNA pairs with G in RNA, so G = 18.5%.
  • G in DNA pairs with C in RNA, so C = 24.1%.
  • A in DNA pairs with U in RNA, so U = 24.6%.
  • T in DNA pairs with A in RNA, so A = 32.8%.

Therefore, the RNA composition will be:

  • G = 18.5%, C = 24.1%, A = 32.8%, U = 24.6%, which matches Option 3.

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