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    Which of the following physiological processes is zinc primarily involved in? (A) Regulation of protein synthesis (B) Activation of vitamin D (C) Co
    Question

    Which of the following physiological processes is zinc primarily involved in?
    (A) Regulation of protein synthesis

    (B) Activation of vitamin D

    (C) Conversion of carbohydrates into energy

    (D) DNA synthesis and cell division

    (E) Modulation of neurotransmitter release
    Choose the correct answer from the options given below:

    A.

    (A), (B) and (D) only

    B.

    (A), (C) and (E) only

    C.

    (A), (D) and (E) only

    D.

    (B), (C) and (D) only

    Correct option is C

    (A) Regulation of protein synthesis
    Zinc is essential for ribosomal structure and function. It acts as a cofactor for numerous enzymes involved in transcription and translation. Hence, correct.

    (D) DNA synthesis and cell division
    Zinc is required for DNA and RNA polymerases and zinc-finger proteins that regulate gene expression. It is essential for growth, tissue repair, and immune function. Hence, correct.

    (E) Modulation of neurotransmitter release
    Zinc acts as a neuromodulator, especially in glutamatergic synapses, influencing synaptic transmission and neuronal signaling. Hence, correct.

    Information Booster:

    • Zinc and Zinc-Finger Proteins: Zinc stabilizes zinc-finger motifs in transcription factors, enabling DNA binding and gene regulation.

    • Immune Function: Zinc deficiency impairs T-cell function and increases susceptibility to infections.

    • Growth and Development: Zinc is critical during pregnancy, childhood, and adolescence due to its role in cell proliferation.

    • Antioxidant Role: Zinc is a structural component of the enzyme superoxide dismutase (SOD), helping protect cells from oxidative stress.

    Additional Knowledge:

    (B) Activation of vitamin D
    Vitamin D activation occurs through hydroxylation in the liver (25-hydroxylation) and kidney (1-α hydroxylation) via cytochrome P450 enzymes. Zinc is not the primary activator. Hence, incorrect.

    (C) Conversion of carbohydrates into energy
    Carbohydrate metabolism mainly depends on magnesium-dependent kinases and B-vitamin–dependent enzymes. Zinc does not have a primary metabolic role here. Hence, incorrect.

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