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    Which of the following is an example of electroneutral pump?
    Question

    Which of the following is an example of electroneutral pump?

    A.

    Ca²⁺-ATPase

    B.

    H⁺/K⁺-ATPase

    C.

    H⁺-PPase

    D.

    H⁺-ATPase

    Correct option is B

    ✅ (b) H⁺/K⁺-ATPase
    · H⁺/K⁺-ATPase exchanges protons (H⁺) for potassium ions (K⁺) across membranes.
    · Since both ions carry a single positive charge, the exchange is electroneutral.
    · Commonly found in the stomach lining for acid secretion and in plants for ionic balance.
    ❌ (a) Ca²⁺-ATPase
    · Transports calcium ions (Ca²⁺) without a counter ion, leading to electrogenic activity.
    · Not electroneutral, as it moves net positive charge.
    ❌ (c) H⁺-PPase
    · H⁺-Pyrophosphatase actively pumps protons across membranes, creating an electrochemical gradient.
    · Electrogenic, not electroneutral.
    ❌ (d) H⁺-ATPase
    · Pumps H⁺ ions across the membrane, contributing to membrane potential generation.
    · Electrogenic pump.

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