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    Which of the following combinations is incompatible?
    Question

    Which of the following combinations is incompatible?

    A.

    A only

    B.

    A and B

    C.

    A and C

    D.

    None of the above

    Correct option is B


    · Normal saline and RL injections are suitable diluents for the intravenous administration of phenytoin.
    · Factors other than pH and co-solvent concentration may affect the stability of phenytoin in dextrose
    · solutions.
    · DNS contains dextrose. So, when phenytoin is mixed in DNS it forms precipitation.
    · The AmphoterIcin B should not be mixed with NS as it will precipitate.
    · The IV line which is used for Amphotericin-B should not be used for any other drug administration.
    · So, option A and B are correct.
    Additional Information:
    · TPN is a mixture of separate components like:
    · Lipid emulsions
    · Dextrose
    · Amino acids
    · Vitamins
    · Electrolytes
    · Minerals
    · Trace elements
    · In TPN ,1 ampule of MVI injection is added to the lipid emulsion (Intralipid 20%) and all other components.

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