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Which of the following combinations is incompatible?
Question

Which of the following combinations is incompatible?

A.

A only

B.

A and B

C.

A and C

D.

None of the above

Correct option is B


· Normal saline and RL injections are suitable diluents for the intravenous administration of phenytoin.
· Factors other than pH and co-solvent concentration may affect the stability of phenytoin in dextrose
· solutions.
· DNS contains dextrose. So, when phenytoin is mixed in DNS it forms precipitation.
· The AmphoterIcin B should not be mixed with NS as it will precipitate.
· The IV line which is used for Amphotericin-B should not be used for any other drug administration.
· So, option A and B are correct.
Additional Information:
· TPN is a mixture of separate components like:
· Lipid emulsions
· Dextrose
· Amino acids
· Vitamins
· Electrolytes
· Minerals
· Trace elements
· In TPN ,1 ampule of MVI injection is added to the lipid emulsion (Intralipid 20%) and all other components.

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