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    Which neurotransmitter is involved in the transmission of impulse at the neuromuscular junction?
    Question

    Which neurotransmitter is involved in the transmission of impulse at the neuromuscular junction?

    A.

    Serotonin

    B.

    Acetylcholine

    C.

    Dopamine

    D.

    Epinephrine

    Correct option is B

    Correct Answer: (b)
    Explanation:
    Acetylcholine (ACh) is the neurotransmitter released at the neuromuscular junction that triggers muscle contraction by depolarizing the muscle membrane.
    Information Booster:
    Action potential reaches the synaptic terminal of motor neuron.
    Synaptic vesicles release acetylcholine into the synaptic cleft.
    ACh binds to receptors on muscle fiber → depolarization → muscle contraction.
    The enzyme acetylcholinesterase quickly hydrolyzes ACh to stop contraction.
    Other neurotransmitters like serotonin, dopamine, and epinephrine act in the brain, not in neuromuscular transmission.
    Additional Information:
    (a) Serotonin – affects mood and sleep, not muscle function.
    (c) Dopamine – related to movement control in CNS (Parkinson’s disease).
    (d) Epinephrine – hormone, not a neurotransmitter at neuromuscular junctions.

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