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Where in the human body does pyruvate undergo aerobic breakdown?
Question

Where in the human body does pyruvate undergo aerobic breakdown?

A.

Mitochondria

B.

Cytoplasm

C.

Muscles

D.

Nucleus

Correct option is A

Sol: The correct answer is (a) Mitochondria

Key points:

  • Mitochondria: Known as the "powerhouses" of the cell, mitochondria are the sites where pyruvate undergoes aerobic breakdown.
  • This process, known as cellular respiration, involves the conversion of pyruvate into carbon dioxide and water while producing ATP (adenosine triphosphate), the energy currency of the cell.
  • ​Mitochondria have a unique structure with two membranes. The inner membrane is folded into structures called cristae, which increase the surface area for energy production.
  • Mitochondria have their own DNA, which is separate from the nuclear DNA. This mitochondrial DNA is inherited maternally (from the mother).

Information booster:

  • Cytoplasm: Glycolysis, the initial breakdown of glucose into pyruvate, occurs in the cytoplasm, but the aerobic breakdown of pyruvate happens in the mitochondria.
  • Muscles: While muscles are the sites of many metabolic processes, the specific aerobic breakdown of pyruvate occurs in the mitochondria within muscle cells.
  • Nucleus: The nucleus houses the cell's genetic material and is not involved in the breakdown of pyruvate.

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