Correct option is B
Introduction:
The question requires determining the correct sequence of events leading to blue baby disease, also known as methemoglobinemia, in human infants. Let's break down the process to identify the correct order.
Information Booster:
The sequence of events for blue baby disease is as follows:
- C. Consumption of nitrate-polluted water: Infants consume water contaminated with high levels of nitrates.
- A. Conversion of nitrate ions to nitrite ions by microorganisms in the human body: The nitrates are converted to nitrites by bacteria in the digestive system.
- B. Oxidation of Fe(II) to Fe(III) in hemoglobin by nitrite ions: The nitrite ions oxidize the iron in hemoglobin from Fe(II) to Fe(III), forming methemoglobin.
- D. Formation of abnormal hemoglobin called methemoglobin: Methemoglobin is formed, which cannot effectively bind oxygen, leading to tissue hypoxia and the characteristic blue discoloration of the skin.
Additional Knowledge:
Understanding the sequence of events in methemoglobinemia is crucial for identifying the cause and implementing preventive measures. The primary source of nitrates is often contaminated water or food, and infants are particularly vulnerable due to their digestive system's immaturity.
The correct sequence is:
- C. Consumption of nitrate-polluted water
- A. Conversion of nitrate ions to nitrite ions by microorganisms in the human body
- B. Oxidation of Fe(II) to Fe(III) in hemoglobin by nitrite ions
- D. Formation of abnormal hemoglobin called methemoglobin
English
10 Questions
20 Marks
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