Three of the following four letter-clusters are alike in a certain way and one is different. Pick the odd one out.
(NOTE: The odd one out is not based on the number of vowels or consonants in the word)

1st + 2nd letter = 27 (alphabet opposites)

3rd letter − 5 = 4th letter

Check options:

A) FUHC → F + U = 27, H − 5 = C 

B) WDYT → W + D = 27, Y − 5 = T 

C) JQLG → J + Q = 27, L − 5 = G 

D) SHQP → S + H = 27, Q − 5 = L ≠ P 

So, SHQP is the odd one out.

Thus, correct option is (d).