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​The following table summarizes the key signaling pathways that orchestrate development, their receptors, transcription effectors, and outputs:​​Which
Question

The following table summarizes the key signaling pathways that orchestrate development, their receptors, transcription effectors, and outputs:

​​Which of the above pathways are correctly matched?

A.

A, C and D

B.

Only B and E

C.

Only A and D

D.

Only C and E

Correct option is D

Explanation-

A. Wnt Pathway
Receptor listed as Thick veins — this is incorrect.
Correct receptor for Wnt: Frizzled
Transcriptional effector β-catenin is correct.
Output “Patterning” is also correct.
Result:Incorrect (because of wrong receptor)

B. Hedgehog Pathway
Receptor listed as Frizzled — Incorrect.
Correct receptor: Patched
Ci/Gli is correct effector.
Output “Growth” is reasonable.
Result:Incorrect (wrong receptor)

C. RTK Pathway
EGFR receptor 
Pointed/Yan effectors 
Output “Morphogenesis” 
Result: Correct

D. TGFβ Pathway
Receptor listed as Patched —  Incorrect.
Correct receptor: TGFβR (type I and II receptors)
Effector NICD —  actually belongs to Notch pathway
Result: Incorrect

E. JNK Pathway
Receptor: TNF 
Effector: Jun/Fos 
Output: Migration 
Result:Correct

Final Answer - Only C and E are correctly depicted.
Option d (Only C and E) is correct.









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