Correct option is D
Explanation-
Asialoglycoprotein (option d) is not a growth factor. It binds to the Asialoglycoprotein receptor (ASGPR), a liver-specific receptor. ASGPR is involved in endocytosis and clearing glycoproteins, but does not have tyrosine kinase activity. So, it does not function as tyrosine kinase
Other options-
Option a - Epidermal Growth Factor (EGF)
Receptor: EGF Receptor (EGFR)
EGFR is a receptor tyrosine kinase (RTK). Upon binding EGF, it undergoes autophosphorylation on tyrosine residues, triggering downstream signaling. It functions as tyrosine kinase
Option b - Platelet Derived Growth Factor (PDGF)
Receptor: PDGF Receptor
It is also a receptor tyrosine kinase. Dimerization and autophosphorylation initiate multiple signaling pathways. It functions as tyrosine kinase
Option c - Insulin
Receptor: Insulin Receptor
Another classic receptor tyrosine kinase (RTK). Binding of insulin activates tyrosine kinase activity in the cytoplasmic domain. It functions as tyrosine kinase .
So, the correct answer is option d - Asialoglycoprotein.
