Study the given pattern carefully and select the numbers from among the given options that would be most appropriate for replacing the question mark (?).

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Given: 

Logic: 1st square × 2nd square = middle Circle 

and 2 is same in each 1st square 

Box I = 2 × 6 = 12 

Box II = 2 × 8 = 16 

Box III. 2 × 10 = 20 

So, correct answer is 2, 10

Thus, correct option is (c).