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Standard base pairing in DNA occurs due to which type of bonding?
Question

Standard base pairing in DNA occurs due to which type of bonding?

A.

Van Der Waals interactions

B.

Ionic bonding

C.

Hydrogen bonding

D.

Covalent bonding

Correct option is C

The correct answer is (c) Hydrogen bonding

Explanation:

  • Standard base pairing in DNA involves specific pairing between nitrogenous bases: Adenine with Thymine and Guanine with Cytosine.
  • These pairs are held together by hydrogen bonds — a type of weak chemical interaction.
  • Adenine (A) forms two hydrogen bonds with Thymine (T).
  • Guanine (G) forms three hydrogen bonds with Cytosine (C).
  • These hydrogen bonds provide stability to the DNA double helix while allowing the strands to separate during replication and transcription.

Information Booster:

  • DNA has a double helix structure as proposed by Watson and Crick in 1953.
  • The sugar-phosphate backbone is held together by covalent bonds, but the base pairs are connected via hydrogen bonds.

Additional Knowledge:

Van Der Waals interactions (Option a)

  • These are weak attractions between molecules or parts of molecules.
  • They help stabilize the stacked bases in DNA but are not responsible for base pairing.

Ionic bonding (Option b)

  • Involves electrostatic attraction between oppositely charged ions.
  • Not involved in the bonding of DNA base pairs.

Covalent bonding (Option d)

  • Strong bonds formed by sharing electrons.
  • Present in the sugar-phosphate backbone of DNA, not between base pairs.

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