Correct option is C
The correct substitution of the highlighted words is (c)
are one of the.
Explanation: The phrase “one off” is incorrect.
The correct expression is “one of the” when referring to a particular item from a group. Also, since “antibiotics” is plural, the verb "are" is correct.
The noun phrase following "one of the" should always be plural.
Grammatical rule used:
·
“One of the + plural noun” is the correct grammatical structure.
· Subject-verb agreement must be maintained.
· "Off" is a preposition of separation and not used in this context; "of" is the correct preposition of inclusion.
Example:
❌ He is one off the best players.
✅ He is one of the best players.