Correct option is D
The option that can be used as a one-word substitute for the given group of words is (d) Matricide.
Matricide is the act of killing one's mother, which is the same as the meaning given in the question.
Meanings of the other options:
Regicide means the act of killing a king or queen.
Homicide means the act of killing a human being.
Uxoricide means the act of killing one's wife.