Select the most appropriate one-word substitution of the given group of words.
Irreverent behaviour toward anything held sacred or concerning God.

Correct option is D

The correct one-word substitution for "Irreverent behaviour toward anything held sacred or concerning God" is Blasphemy (D).

• Blasphemy: Act of showing disrespect or lack of reverence toward God or sacred things.
• Hindi meaning: ईशनिंदा
• Example: His comments were considered blasphemy by the religious community.

Meanings of other options:
 Agnosticism - Agnosticism is the belief that the existence of God or the divine is unknown or unknowable.
 Pantheism - Pantheism is the belief that the divine is present in everything in the universe and that the universe itself is divine.
 Theism - Theism is the belief in the existence of a god or gods who are actively involved in the world and in human affairs.