Correct option is D
Blessed means to be favored or granted with good fortune, divine help, or protection.
Cursed - to invoke or wish evil upon someone or something.
Therefore, option (d) is the correct antonym of the highlighted word in the given sentence.
Antonyms: cursed, unlucky, unfortunate, doomed.
Synonyms: favored, fortunate, happy, prosperous.
Meanings of the given words:
Appointed - to assign a duty or position to someone.
Produced - to create something through physical or mental effort.
Applied - to put into operation or use for a specific purpose.