__________reduce (s) the size of large fat globules, allowing enzymes to work more effectively.

Correct option is C

The correct answer is (c) Bile salts.

• Bile Salts are produced in the liver, directly from cholesterol. Bile salts are important in solubilizing dietary fats in the watery environment of the small intestine.
• Once produced, but before being secreted into the gallbladder or digestive system, bile salts are often bonded to glycine or taurine.
  

Information Booster:

• Succus entericus is the alkaline secretion produced by glands in the wall of the duodenum, consisting of water, mucoproteins and hydrogen carbonate ions.
• It helps to counteract the highly acidic and proteolytic chyme entering the small intestine from the stomach, and thus protects the duodenum from damage.
• Pancreatic juice is a fluid produced by the pancreas that contains digestive enzymes to help break down food: Lipase: Works with bile to break down fats Protease: Breaks down proteins and protects against intestinal germs Amylase: Breaks down starches into sugar for energy. Pancreatic juice has a pH of 7.5–8.0.