Pyruvate generated by glycolysis is converted to acetyl-coenzyme A, which is metabolized by the citric acid cycle generating energy-rich molecules. From the choices given below, select the right combination of these molecules produced from one molecule of acetyl-CoA.

Cyanide, a chemical warfare agent, is toxic because it:​

A. binds to the heme a3 in mitochondrial cytochrome c oxidase (in complex IV)

B. inhibits electron transport and thus oxidative phosphorylation
C. directly blocks mitochondrial DNA replication
D. blocks the protein trafficking inside the mitochondria by affecting TIM and TOM channels

Choose the combination with all correct statements.

Following statements are made regarding glycogen phosphorylase and glycogen synthase activities in relation to their phosphorylation status:

A. Phosphorylation of glycogen phosphorylase increases its activity
B. Phosphorylation of glycogen phosphorylase decreases its activity
C. Phosphorylation of glycogen synthase increases its activity
D. Phosphorylation of glycogen synthase decreases its activity

Which one of the following is a combination of correct statements?

The interconversion of fructose 6-phosphate to fructose 1,6-bisphosphate is a critical step in central metabolism in plants. Followings are certain statements regarding this interconversion:

A. Phosphofructokinase catalyzes the C6 phosphorylation of fructose 6-phosphate.
B. Plastid phosphofructokinase is activated by Pi while cytosolic phosphofructokinase is activated by phosphoenolpyruvate.
C. Cytosolic fructose 1,6-bisphosphatase is strongly inhibited by fructose 2,6-bisphosphate.
D. Pyrophosphate-dependent phosphofructokinase catalyzes a reversible reaction of interconversion of fructose 6-phosphate to fructose 1,6-bisphosphate.

Which one of the following options is a combination of all correct statements?

​Skeletal muscle cells need to convert pyruvate to lactate while sustaining anaerobic respiration to:​

​The citric acid cycle (TCA) operates only in the presence of molecular oxygen $$(O_2)$$  This is because:​

​Which one of the following statements with regard to glyoxylate cycle is INCORRECT?​

In yeast, under anaerobic conditions, pyruvate is fermented to ethanol through two steps: decarboxylation of pyruvate to acetaldehyde and NADH-mediated reduction of acetaldehyde to ethanol. The mammalian liver also expresses alcohol dehydrogenase (Liver ADH: L-ADH). From the options given below, choose the one that best explains the physiological significance of L-ADH in the absence of fermentation in the liver.​

Pyruvate generated by glycolysis is converted to acetyl-coenzyme A, which is metabolized by the citric acid cycle generating energy-rich molecules. From the choices given below, select the right combination of these molecules produced from one molecule of acetyl-CoA.

For the coupled reaction given below, the equilibrium constants 

(Keq)(K_{eq})(Keq​) for equation $[1]$ and equation $[2]$ are 270 and 890, respectively.

Glucose 6-phosphate+H2O→Glucose+Pi[1]\text{Glucose 6-phosphate} + H_2O \rightarrow \text{Glucose} + P_i \quad [1]Glucose 6-phosphate+H2​O→Glucose+Pi​[1]ATP+Glucose→ADP+Glucose 6-phosphate[2]\text{ATP} + \text{Glucose} \rightarrow \text{ADP} + \text{Glucose 6-phosphate} \quad [2]

ATP+Glucose→ADP+Glucose 6-phosphate[2]

The standard free energy of hydrolysis of ATP at 25°C is:

The following statements are made regarding the conversion of pyruvate to acetyl-CoA going from glycolysis to the citric acid cycle:

A. Oxidation of pyruvate to acetyl-CoA is reversible.
B. Pyruvate is transported into the mitochondrion by a transporter.
C. Pyruvate is carboxylated by pyruvate dehydrogenase.
D. Acetyl lipoamide reacts with coenzyme A to form acetyl-CoA.
E.The flavoprotein, dihydrolipoyl dehydrogenase, containing flavin adenine dinucleotide (FAD), is involved in the conversion of pyruvate to acetyl-CoA.

Which one of the following options represents the combination of all correct statements?