Correct option is A
The correct answer is (a) Discoveries concerning the genomes of extinct hominins and human evolution
Explanation:
- Svante Pääbo achieved the seemingly impossible task of sequencing the genome of the Neanderthal, an extinct relative of present-day humans.
- He also discovered a previously unknown hominin, Denisova.
- His work established an entirely new scientific discipline: Paleogenomics.
- He found that gene transfer had occurred from these extinct hominins to Homo sapiens following the migration out of Africa.
- This ancient gene flow has physiological relevance today, such as affecting our immune system's response to infections.
Information Booster:
- He is the director at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.
- Pääbo's father, Sune Bergström, also won a Nobel Prize in Medicine (1982).
Additional Knowledge:
Mapping the human proteome (Option b)
- Incorrect; while significant, this was not the basis for the 2022 Nobel Prize.
Stem cell research (Option c)
- Incorrect; Shinya Yamanaka and John Gurdon won in 2012 for this field.
Synthetic genome (Option d)
- Incorrect; J. Craig Venter is a key figure here, but it has not been awarded a Nobel Prize for Medicine recently.
So the correct answer is (a)