Correct option is A
Series: Z1A, X2D, V6G, T21J, R88M, P445P, ?

Letters: −2 each side
Numbers: ×n + pattern increasing
Last letter: +3
Z, X, V, T, R, P → each −2 → next = N
A, D, G, J, M, P → each +3 → next = S
1 → 2 → 6 → 21 → 88 → 445
Pattern:
1×1+1=2
2×2+2=6
6×3+3=21
21×4+4=88
88×5+5=445
Next:
445×6 + 6 = 2676
N2676S
A