Fill in the blank with the appropriate preposition:
He is angry ___ me.

Correct option is C

The correct preposition is "with" because it is commonly used to describe anger directed toward a person or group. "Angry with" is the standard construction in such contexts.
Information Booster:
1. On/Upon: Used for physical positions or occasions, not emotions.
2. With: Indicates anger directed at someone.
3. At: Sometimes used, but generally for anger toward situations, not people.