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    ​At which one of the following electron transport chain complexes does Antimycin A typically inhibit the respiratory chain?​
    Question

    At which one of the following electron transport chain complexes does Antimycin A typically inhibit the respiratory chain?

    A.

    Complex I

    B.

    Complex II

    C.

    Complex III

    D.

    Complex IV

    Correct option is C

    Explanation-

    ​Antimycin A inhibits the electron transport chain at Complex III (cytochrome bc1 complex). It blocks electron transfer from cytochrome b to cytochrome c1, thereby halting ATP production and respiration.
    So, the correct answer is option 3: Complex III 

    Incorrect options-

    Option 1: Complex I (NADH dehydrogenase)
    Antimycin A does not interact with Complex I. Instead, inhibitors like rotenone and piericidin A affect Complex I.

    Option 2: Complex II (Succinate dehydrogenase)
    Antimycin A has no effect on Complex II. Instead, inhibitors such as thenoyltrifluoroacetone (TTFA) or malonate act on Complex II.

    Option 4: Complex IV (Cytochrome c oxidase)
    Antimycin A does not inhibit Complex IV. Inhibitors of Complex IV include cyanide, carbon monoxide (CO), and azide.

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