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Among the following select the correct statements:In reversible competitive enzyme inhibition(i) The inhibitor bears structural resemblance to substra
Question

Among the following select the correct statements:
In reversible competitive enzyme inhibition
(i) The inhibitor bears structural resemblance to substrate.
(ii) Both Km and Vmax are increased.
(iii) The inhibitor does not bear structural resemblance to substrate.
(iv) Km is increased whereas Vmax remains unchanged.

A.

(i) and (iv)

B.

(ii) and (i)

C.

(iii) and (iv)

D.

(ii) and (iii)

E.

None of the above

Correct option is A

In competitive inhibition, the inhibitor mimics the substrate (structural resemblance), so it competes for the active site.
Km increases (more substrate needed),
Vmax remains unchanged (can be reached by increasing substrate concentration).
Hence, correct statements are (i) and (iv).

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