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    ​Absorbed monosaccharides in intestinal epithelial cells exit via which one of the following transporters?​
    Question

    Absorbed monosaccharides in intestinal epithelial cells exit via which one of the following transporters?

    A.

    GLUT2

    B.

    GLUT3

    C.

    GLUT4

    D.

    GLUT5

    Correct option is A

    Explanation -

    Option a - GLUT2 

    It facilitates the transport of glucose, galactose, and fructose from the basolateral membrane of intestinal epithelial cells into the bloodstream. It is present in  basolateral membrane of enterocytes (intestinal cells). It transport through  facilitated diffusion (passive).

    Option b  -  GLUT3
    GLUT 3 is high-affinity glucose transporter, mainly expressed in neurons. It is not  present in intestinal epithelial cells. It plays crucial role in glucose uptake in cells with high glucose demand (e.g., brain).
    It is not  involved in monosaccharide export from intestinal cells.

    Option c  - GLUT4
    GLUT 4  is insulin-regulated glucose transporter found in adipose tissue and muscle. It is not found in intestinal epithelial cells.

    Option d - GLUT5
    GLUT 5 is specialized for fructose transport. It is present in apical membrane of intestinal epithelial cells. It helps in fructose uptake into intestinal cells from the lumen. It is responsible for fructose entry, not exit.

    So, the correct answer is option a - GLUT2
    GLUT2 is the transporter responsible for exporting absorbed monosaccharides from intestinal epithelial cells into the bloodstream.

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